Researchers have produced targeted, modifiable nanoparticles which could be the revolutionary future as they could be combined with dosages as a form of drug delivery to fight cancer. The research collaboration has formed nanoparticles consisting of antibody fragments that have advanced them to deliver drugs and target the most dangerous and fatal element, the epidermal growth factor receptor (EGFR) of the cancer cells. The scientists are very optimistic about the development and believe this new technology infused with therapeutics may be the future for all anti-cancer treatments.
Two scientists from Germany combined to modify the carrier molecules to produce nanoparticle that targets both the Vitro as well as the Vivo cancer cells, the scientists procured biocompatible dendritic polyglycerol nanoparticles, which they further modified to introduce a cancer-targeting function in the molecules. The research institute further explained that the scientists have attached an antibody fragment to the carrier molecule as the targeting entity on EGFR (On the surface of tumors)
Alongside the antibodies, the molecule was also infused with the dye elements, the dye particle emits in the near spectrum that penetrates the tissue and due to the dye, and the location of the molecule can be visualized using the particular type of microscope. Copper-64 emits radiation which can be detected by PET (Positron emission tomography) scanner. The signals captured by the scanner can be transformed into a 3-dimensional image (3D image), that can help understand the position and distribution of particles in the organism.
In the future, the researchers want to discover if they are capable of carrying other components, such as an active pharmaceutical ingredient (API) or drug. This can be the future for destroying the tumor cells and cancer elements. They also have a plan in place to experiment with antibody bits to target other cancer receptors to enhance the effectiveness of these nanoparticles.