How Big Pharma is changing the rules and making People worse off

How Big Pharma is changing the rules and making People worse off

Big Pharma spends a small fortune each year lobbying politicians to make sure we can’t import prescription drugs from Canada, but they are more than happy to sell us contaminated drugs from countries with poor production standards and exploitable labor ensuring high profit margins.

A dangerous substance that does not belong anywhere near the drug known as NDMA was first found in some blood pressure drugs in 2018, and the FDA released a warning and wrote a letter of complaint to the manufacturer of raw materials to Big Pharma. It turns out the meds follow the very common pattern of raw ingredients coming from China and manufactured in India. And big companies sell them to U.S. consumers for obscenely high prices.

More recently, NDMA contamination has triggered a nationwide recall of Zantac’s popular anti-heartburn drug and all its generic versions.

And now the most widely prescribed drug in the world is being contaminated with NDMA, which is used to treat and prevent Type 2 diabetes called metformin.

According to the World Health Organization, NDMA (N-Nitrosodimethylamine) is generated by “dimethylhydrazine degradation (a part of rocket fuel) and several other industrial processes. It is also a contaminant in some pesticides.’

And, at least for humans and other mammals, it is one of the most active carcinogens in the world. Our livers contain an enzyme that transforms it to methyldiazonium, which then leads to O6-methylguanine, both of which modify a process called methylation at the cellular level which is a turbocharger for cancer.

Because it is such a potent biological agent, NDMA is also extremely poisonous; a Chinese student of medicine put a few drops into the water of his roommate and killed him. Ditto for a Canadian graduate student who injected it into an apple pie for a colleague.

It is so toxic that the FDA has set the “appropriate” volume for human daily intake at 96 nanograms, or 0.000096 of 1 milligram (about one milligram is a single grain of salt). In some of the blood pressure medication’s generic brands, only one tablet has been found to have NDMA levels nearly 20 times higher than the “appropriate” 96 nanograms, and almost all were regular medications.

 

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