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Muscles Can now Prevent Muscular Dystrophy Through Stem Cells

Muscles tend to lose their strength and flexibility through the aging of humans. As we age, muscles lose their ability to hold our bodies strong which affects our motion. This has encouraged many teams worldwide to find the reason behind the weakness that affects humans and ways to prevent it or slow down the decay of tissues.

A new study conducted by a team from Sanford Burnham Prebys have found a way to boost stem cells of muscles to help stop it from aging and other muscle disorders including dystrophy. The study includes a newly discovered pathway which uses certain proteins called Stat3 and Fam3a which affects stem muscles. Accordingly, they force muscles to get weaker and lose their strength. Being able to control stem cells through new treatments and regulating the levels of the proteins will help slow down or even stop the decaying of tissue muscles and losing their strength.

The study was published in the journal of Nature Communication journal, by PhD holder and an associate professor in the Development, Aging and Regeneration Program at Sanford Burnham Prebys called Alessandra Sacco. He commented on his results saying, “Muscle stem cells can ‘burn out’ trying to regenerate tissue during the natural aging process or due to chronic muscle disease. We believe we have found promising drug targets that direct muscle stem cells to ‘make the right decision’ and stimulate muscle repair, potentially helping muscle tissue regeneration and maintaining tissue function in chronic conditions such as muscular dystrophy and aging.”

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