Team based at Kyoto University gets approval from health ministry for knee joint transplant by iPS-derived cartilage

Team based at Kyoto University gets approval from health ministry for knee joint transplant by iPS-derived cartilage

On Friday, a panel of experts from the health ministry permitted a clinical study program put forward by a group from Kyoto University for the transplantation of cartilage generated from induced pluripotent stem cells to injured joints in the knee.

The team comprises of Professor Noriyuki Tsumaki and other members. Together, they are intending to generate cartilage having a diameter of between 2 millimeters and 3 millimeters by making us iPS cells kept at Kyoto University’s Center for iPS Cell Research and Application.

This year, the group hopes to conduct its very first transplant. Following a clinical trial conducted by Asahi Kasei Corp., which backs the project, the team intends to make the technology available for practical use by 2029.

4 individuals between the ages of 20 and 70 will go through the transplant operations with the help of iPS cell-derived cartilage for their injured knee joints. In these individuals, the damaged are ranges between 1 and 5 centimeters. Presently, the team does not intend to look for increased number of patients for its program.

For about one year following the operation, the team will keep a check on the 4 partaking individuals to keep a look out for potential growth of tumors. The transplanted material will fuse with the cartilage already present, provided that the operation is a successful one.

On Friday, while in talks with a news conference at the Kyoto University Hospital, Professor Noriyuki Tsumaki stated how there are numerous patients undergoing inconvenience because of damaged cartilage. Tsumaki stated how they would work hard so they are able to deliver therapy methods.

The Kyoto University team also, eventually, intends to apply this therapy to individuals who have osteoarthritis.

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